DS Biopharma (DS) Announces Spin-Out Company Focused on Fibrotic Conditions

Dublin, Ireland, 22 August 2016: DS Biopharma (DS), a privately held drug discovery and development company with industry-leading expertise in lipid science, today announces the launch of a spinout company focused solely on fibrotic conditions such as non-alcoholic steatohepatitis (NASH) .

The new company, Afimmune, will continue the clinical development of DS102, a novel, anti-fibrotic compound. The company will study DS102 in NASH. Afimmune has a number of other compounds in pre-clinical development.

DS Biopharma will focus on the development of DS107, an anti-inflammatory compound for atopic dermatitis and pruritus and DS109 for other inflammatory skin disorders such as acne.

Dr. John Climax, Executive Chairman of DS Biopharma, said: ‘By spinning out DS102 into a new company, DS Biopharma can direct its full attention to developing products for inflammatory skin conditions whereas Afimmune will focus on fibrotic conditions .’

Afimmune plans to start a Phase IIa study with DS102 in NASH patients later this year, this compound having been shown to be safe and well tolerated in a Phase I trial.

About DS Biopharma

DS Biopharma, headquartered in Dublin, Ireland, is a privately held drug discovery and development company working on new medicines that improve the quality of life for people with diseases for which existing therapies are ineffective or unsafe. DS has developed a proprietary bioactive lipid technology platform. The Company is developing Topical DS107 for mild to moderate atopic dermatitis and Oral DS107 for moderate to severe atopic dermatitis. Both Topical and Oral DS107 are planned to begin separate Phase IIb clinical studies later this year. In addition the Company expects to bring DS109, which is being explored as a treatment for inflammatory skin disorders, into the clinic later this year.



DS Biopharma: investorrelations@dsbiopharma.com, +35312933590