Dr. John Climax, Chairman & Chief Executive Officer

Dr. John Climax, is a co-founder of ICON plc, one of the world’s largest contract research organizations.  Dr. Climax was ICON plc’s Chairman from November 2002 to December 2009. Prior to that, from June 1990 to November 2002 he served as Chief Executive of the Company.  He has over 30 years of experience in the contract research industry globally.  John received his primary degree in pharmacy in 1977 from the University of Singapore, his masters in applied pharmacology in 1979 from the University of Wales and his PhD in clinical pharmacology from the National University of Ireland in 1982. He has authored a significant number of papers and presentations, and is an adjunct professor at the Royal College of Surgeons in Ireland. He is named inventor on a number of patents.

Dr. Ronan Lambe, Non-Executive Director

Dr. Lambe, is a co-founder of ICON plc, one of the world’s largest contract clinical research organizations. He has over 35 years of experience in the contract research industry.  Dr. Lambe attended the National University of Ireland where he received his Bachelor of Science degree in chemistry in 1959, his masters in biochemistry in 1962 and his PhD. in pharmacology in 1976.

Dr. Mehar Manku, Chief Science Officer

Dr. Mehar S. Manku has been active in lipid research for more than thirty years. During his lengthy career, Dr. Manku has authored some 250 scientific and technical papers and is the named inventor on 65 patents. Dr. Manku served for 35 years as an executive editor of the fatty acid journal Prostaglandin, Leukotrienes and Essential Fatty Acids. (PLEFAs). He was appointed editor in 2003 and held the position until late 2010, when he stood down to become Emeritus Editor. Recently, he was appointed Editor-in-Chief of Medical Hypotheses. Dr. Manku worked in several research and development roles at Amarin Corporation from November 2004 to April 2010. Prior to Amarin, Dr. Manku worked in various scientific and technical roles at Scotia Pharmaceuticals Ltd and later at Laxdale Ltd (1979 – 2001).

Ms. Jane Hollingsworth, Non-Executive Director

Non-Executive Director Science / Strategy


Jane is currently Executive Chair of Talee Bio, a gene therapy company focused on cystic fibrosis as well as diseases of the lung and Managing Partner of Militia Hill Ventures.

Jane is co-founder and former CEO of NuPathe Inc. (NASDAQ: PATH), a biopharmaceutical company focused on diseases of the central nervous system which was sold to Teva in 2014. She also co-founded and served as Executive Vice President of Auxilium Pharmaceuticals (NASDAQ: AUXL), a biopharmaceutical company focused on urology which was sold to Endo Pharmaceuticals in 2015. Prior to launching and leading these two successful biopharmaceutical companies, Jane was VP, Secretary & General Counsel of IBAH, Inc. (NASDAQ: IBAH), a multinational clinical research organization.

Mr. Alan Cooke ACA, Non-Executive Director

Mr. Alan Cooke, has extensive experience in the healthcare and pharmaceutical market, and previously held positions of Chief Finanical Officer and Chief Executive Officer of the Trulife Group Limited.

Mr. Cooke has held a number of senior positions including President, Chief Operating Officer and Chief Financial Officer of Amarin Corporation plc. and Vice President, Global Strategic Planning of Elan Corporation plc. Mr. Cooke is Chairman of the Trinity College Institute of Neuroscience.

Mr. Leopoldo Zambeletti, Non-Executive Director

Mr. Zambeletti is a highly respected figure within the life sciences sector. During a 19 year career as an investment banker, he led the European Healthcare Investment team at JP Morgan for eight years before taking up the same position at Credit Suisse for a further five years. Since 2013 Mr Zambeletti has been an independent strategic advisor to life science companies on Merger and Acquisitions, out-licensing deals and financing strategy. He is a Non-Executive Director of Nogra Pharma, Advanced Accelerator Applications, Faron Pharmaceuticals, Summit Therapeutics plc. and an advisor and co-founder to the US medtech company Qardio. He serves as a trustee to Barts and the London Charity, which helps to fund the hospitals of the Barts NHS Trust including St. Bartholomew, the Royal London and the London Chest Hospitals, and he is a founder of the cultural initiative 5×15 Italy. Mr Zambeletti started his career at KPMG as an accountant.

Dr. Markus Weissbach, Chief Operating Officer and Medical Director

Dr Markus Weissbach has more than 25 years working experience in the international pharmaceutical, biotech and CRO industry. His previous appointments include Chief Medical Officer Europe at Novartis Vaccines and Diagnostics; Executive Chairman, CEO and President of Averion International Corp; President of ICON Clinical Research Plc., Europe; Director Clinical Research and Development at Takeda Euro R&D and International Medical Director at Knoll AG. Dr. Weissbach has served as advisory/supervisory board member for companies such as CytoTools Biotech AG, Vasopharm, Cardiorentis, BernaBiotech, Sunesis, Merck KGaA, and Otsuka. He has been instrumental in the successful NDAs and market launch of several NCEs and biologics in different indications. Dr. Weissbach is very well connected to academia & KOLs in different therapeutic areas such as, cardiology, vaccines, oncology, CNS, infectious and autoimmune diseases and has profound experience in dealing and negotiating with regulatory authorities in Europe and the USA.

Mr. Mark O'Neill, ACA, Chief Financial Officer

Mr. O’Neill heads up the Finance division in DS Biopharma. Mr. O’Neill has a wealth of experience in bringing products to market and company financing. Prior to joining DS Biopharma, he held a number of senior financial and operational positions in organisations ranging from startup enterprises to large global established companies. A Commerce graduate of University College Dublin and qualified Chartered Accountant with Deloitte, Mr. O’Neill also holds a Masters of Accounting from the Smurfit School of Business and a Diploma in Corporate Finance from the Institute of Chartered Accountants.

Dr. David Coughlan, Vice President Technical Operations

Dr. David Coughlan has over 15 years experience in pharmaceutical research and development. Dr. Coughlan joined DS Biopharma from Merrion Pharmaceuticals plc where he held a number of senior technical and management positions in the product development arena including Director of Formulations. Dr. Coughlan has significant experience in the management of a variety of product development programmes. He began his career with Élan Corporation plc. Dr. Coughlan holds a B.Sc. in Pharmacy and PhD in Pharmaceutics from Trinity College Dublin, Ireland. He is a registered pharmacist and has authored numerous research papers and abstracts within the pharmaceutical field. He is a named inventor on a number of patents.

Ms. Josephine Coyle, Vice President QA and Regulatory Compliance

Josephine Coyle has over 25 years experience in the Clinical Research Industry, with a track record of delivering high quality and regulatory compliance. Jo started her career in the Clinical Laboratory field and prior to joining DS Biopharma, held various senior global QA positions at ICON Plc, most recently serving as VP of Corporate QA. Areas of expertise include Quality Assurance, Clinical Laboratory Management, Quality System Development (GXP, ISO 9000, CAP) and Computer System Validation. Jo has a Masters Degree in quality management from the University of Wolverhampton.